Alpha Brain Clinical Study Shown to Increase Memory, Focus, and Executive Function
AUSTIN, TX (February 24, 2016) – The results and methodologies from the Alpha BRAIN clinical trial were accepted and published by the Journal of Human Psychopharmacology: Clinical and Experimental.
The randomized, double blind, placebo-controlled study conducted by the Boston Center for Memory assigned 63 participants to take either one serving of Alpha Brain or a placebo for 45 days.
Subjects were evaluated before and after the supplementation period using validated neuropsychological assessments. The demographics of the subject group included mostly healthy 18 to 35-year-old males and females with above average education and IQ score.
The results indicate that supplementation with Alpha BRAIN can improve memory and executive function in healthy adults.
There were no noticeable differences in cognitive performance nor demographics between the two groups at the beginning of the study.
The results indicate that supplementation with Alpha BRAIN can improve memory and executive function in healthy adults. Although both groups improved over time, the performance on two assessments in the Alpha BRAIN group exceeded the placebo group to a clear statistically significant margin.
Specifically, those who took Alpha BRAIN improved their ability to recall a list of words recited to them 20 minutes earlier, thereby improving their delayed verbal recall.
The Alpha BRAIN group also significantly outperformed the placebo group in a test that asks participants to draw a line connecting alternating numbers and letters in sequence as quickly as possible.
Faster completion times reflect better executive function or a set of higher cognitive processes that rely upon attention, memory, inhibition and mental flexibility.
The CEO of Onnit Labs, Aubrey Marcus, commented, “To see our Alpha BRAIN trial published in a major journal is a significant milestone. To know that the results and methodologies of the study were validated through the rigorous peer review process supports a scientific opinion that we are offering the absolute best nootropic supplement utilizing earth grown nutrients in existence. Onnit will continue its mission to provide primary, peer-reviewed research on all of its flagship formulas.”
No significant side effects were reported in either group and study compliance was high, indicating overall good tolerability with daily Alpha BRAIN use. Furthermore, there were no differences in sleep quality between the two groups.
An abstract with the full study link can be viewed here on PubMed.
In addition to the neuropsychological assessment, a compelling biomarker was added to the study protocol. A subset of the subjects were recruited to participate in electroencephalographic (EEG) brain recording at three time points:
Baseline, 1 hour after their first dose, and after the full 45 day study period.
The purpose of this design was to compare a single dose to a prolonged supplementation of Alpha BRAIN to monitor changes in brain activity.
Remarkably, those taking Alpha BRAIN exhibited statistically faster processing speed and greater response detection amplitudes after both a single dose and 45 days compared to their placebo counterparts.
This data was presented separately and recently published as an abstract in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association available here.
The lead investigator on the study, Todd Solomon, PhD, commented, “Having the manuscript of the study accepted in a peer-reviewed journal such as Human Psychopharmacology further validates not only the result of the study, but the scientific rigor that was utilized.”
Onnit Labs’ contribution to the scientific literature sets a precedent for the nutritional supplement industry. To take the previous knowledge of nutritional products and formulate compounds in a way that has proven benefits on cognitive performance is a milestone achievement.
The data has attracted attention of various researchers with new scopes of study, such as the US Army and the Alzheimer’s Association. Onnit will continue to fund research that is valuable to both consumers of Onnit products and the larger scientific community.
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